Lab for Thin Films - Nanobiomaterials - Nanosystems - Nanometrology

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LTFN makes use of cutting-edge equipment and 2 Pilot Lines for nanomaterials synthesis, characterization and in vitro studies. Facilities include cell culture, coating and 3D electrospraying deposition and printing systems, while a fully equipped chemical laboratory is available for nanoparticles, nanofibers and nanofilms development and biofunctionalization.
This research field, includes the design, development, validation and production of drug delivery nanosystems and biomedical devices, smart nanomaterials, nanoporous delivery platforms, scaffolds for tissue regeneration, nanoparticles for in vivo diagnostics, treatment of diseases etc.

Products & Applications

  • Biodegradable nanoparticles with Anti-oxidant drugs for reduction of Oxidative Stress
  • Biodegradable scaffolds for Drug Delivery and Tissue Engineering (CVDs, Osteoathritis, Wound healing, etc.)
  • Nanoporous materials loaded with Drugs, 3D Printing and 3D BioPrinting
  • Biodegradable nanosystems deposited onto implants (Stents and Orthopedics)
  • Nanoparticles onto surfaces to enhance antimicrobial and antibacterial behavior

The recently established 3D-Bioprinting Laboratory is located at the facilities of the LTFN Nanomedicine & Nanobiotechnology Group. It is run by the multidisciplinary research members, who have at their disposal state-of-the-art 3D-Bioprinting, 3D-Printing and other 3D-scaffold manufacturing technologies for the production of complex structures as well as characterization tools for the static and dynamic in vitro testing of the cell seeded structures.

The facility focuses initially in orthopaedics aiming to the regeneration of patient specific osteochondral defects, cartilage, ligaments and joints. Working in close collaboration with other groups of the LTFN the specific group exploits establishmed know-how on:

  • Design, development, validation and production of nano-bio-materials as scaffolds
  • Biodegradable nanoparticles as drug carriers for their selective spatial distribution within the 3D-Bioprinted structures
  • Biodegradable nanofibers for the enhancement of vascularization
  • Organic and printed electronics for the innovative introduction of sensing/biosensing elements and intervening methods in selected areas of the 3D-Bioprinted structures
  • Drug delivery systems loaded with growth factors for the spatial biofunctionalization as required

3dprinter 01  3dprinter 02

Equipment for the in-vitro biological and cytocompatibility characterization

incub1  incub2

CO2 Incubator

for the maintenance of cell cultures (human and animal) and cytocompatibility protocols.

 

hood1  hood2

Laminar Hood

for the preperation and implementation of various cytocompatibility tests and cell sub-culturing.

 

centri1  centri2

Centrifuge

commonly used for the separation of components in a complex mixture. Wide variety of use as it concerns separation of organic phases of nanoparticles as well as sedimentation of cells' pellet.

 

Elisa Plate Reader

 

optical

Optical Microscope

used on a large scale in the studies od cell structure's evaluation morphology, nanostructures like fiber-based scaffolds in order to justify their surface topography characteristics.

 

It is a nanofabrication process for the spraying of natural, synthetic polymers and composite solutions to form nanostructured coatings (either fibres or particles) deposited on a conductive substrate using electrostatic force.

esd

Widely used technique for the production of thin films of polymeric materials on different surfaces in order to produce homogenous coating of high thickness and uniformity for a long time. Variety application in sensors, membranes, hydrogels and antimicrobial surfaces.

System with the ability to isolate and maintain cells or even whole tissues for a long time, without the susceptible to damage caused by chemical reactivity, by cooling and freezing at low temperatures (-80oC).

Basic tool for the evaluation of cells’ viability proliferation’s behavior. Luminometer can measure UV and visible light, thus provide useful informationσ about light absorbance, that is used for a wide variety of assays including MTT assays, ATP assays, cellular luminescence, enzyme activity assays, and cell-based assays for drug delivery.

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At LTFN we consider the privacy of our visitors to be extremely important. This privacy policy document describes in detail the types of personal information is collected and recorded by LTFN and how we use it.

If you require any more information or have any questions about our privacy policy, please feel free to contact us by email.
This website is operated by LTFN web administration group, which belongs to the Nanotechnology Lab LTFN, in Aristotle University of Thessaloniki-Greece.
When we say ‘we’, ‘us’ or ‘LTFN’ it is because that is who we are and we own and run the website.

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We collect information from you when you contact us via form, as appropriate. You do not have to give us any personal information in order to use the website. However, if you wish to take advantage of some personalized services we offer, you will need to provide us with certain information about yourself. For example if you wish to contact us or send us a request, we will collect some or all of the following personal data from you: name, email, affiliation you belong/work etc.
We require this information to understand your needs and provide you with a better service, and in particular for the following reasons: internal record keeping, to improve our services, send promotional emails about news for LTFN’s activities or to manage your contact request.
All the data is stored in the hosting service’s infrastructure and can be accessed by LTFN’s administration group or the hosting service’s administration.

Security
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Children's Information
We believe it is important to provide added protection for children online. We encourage parents and guardians to spend time online with their children to observe, participate in and/or monitor and guide their online activity. LTFN does not knowingly collect any personally identifiable information from children under the age of 16. If a parent or guardian believes that LTFN has in its database the personally-identifiable information of a child under the age of 16, please contact us immediately (using the contact in the first paragraph) and we will use our best efforts to promptly remove such information from our records.

Controlling your personal information
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We will not sell, distribute or lease your personal information to third parties unless we have your permission or are required by law to do so. We may use your personal information to send you promotional information about third parties which we think you may find interesting if you tell us that you wish this to happen.
You may request details of personal information which we hold about you. If you would like a copy of the information held on you please email us.
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You also have the right to ask us to delete the personal information we hold for you.

Online Privacy Policy Only
This privacy policy applies only to our online activities and is valid for visitors to our website and regarding information shared and/or collected there. This policy does not apply to any information collected offline or via channels other than this website.

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By using our website, you hereby consent to our privacy policy and agree to its terms. If you have any questions about how we handle user data and personal information, feel free to contact us.

Update
This Privacy Policy was last updated on: Tuesday, May 22nd, 2018.
Should we update, amend or make any changes to our privacy policy, those changes will be posted here.